Role of endothelin receptor A and NADPH oxidase in vascular abnormalities

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Role of endothelin receptor A and NADPH oxidase in vascular abnormalities

Vascular dilatation is critically impaired in many diseases and is encountered by an upregulated endothelin receptor A (ETA) in the vasculature in association with a decline in nitric oxide bioavailability. Diabetic vasculopathy is characterized as a compromised vascular dilatation, implicated in many diabetic complications. It appears to be activated ETA and NADPH (nicotinamide adenine dinucle...

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ژورنال

عنوان ژورنال: Vascular Health and Risk Management

سال: 2010

ISSN: 1178-2048

DOI: 10.2147/vhrm.s6556